Role of Intermittent Fasting on Disease Severity and Quality of Life in Psoriasis and Psoriatic Arthritis: A Systematic Review
Abstract
Psoriasis and psoriatic arthritis (PsA) have a strong association with obesity and metabolic syndrome. Despite patient interest in non-pharmacologic methods to treat psoriasis and manage overall health, there is insufficient data available to guide dietary counseling. This study aimed to identify the role of a popular anti-inflammatory diet known as intermittent fasting (IF) in management of psoriasis and PsA. A systematic review was conducted on PubMed and Embase, which yielded 34 total studies. A total of 14 articles were critically appraised by four investigators. In addition to affecting weight management in patients, IF had direct effects in both psoriasis and PsA disease activity, as well as patient quality of life (QoL). The effects of IF encompass mechanisms independent of weight loss alone. Across all studies, IF was correlated with improvements in patient-reported outcomes of disease activity and quality of life, biometric measurements, and inflammatory laboratory values. This article serves as the first summary of studies that demonstrate a relationship between IF and the disease course of psoriasis and PsA.
Keywords: psoriasis, psoriatic arthritis, intermittent fasting, diet, holistic, alternative medicine
How to Cite:
Rose, L., Gray, A. N., Jolley, D., Schildmeyer, A., Bubic, B., Kaffenberger, J. & Kaffenberger, B. H., (2026) “Role of Intermittent Fasting on Disease Severity and Quality of Life in Psoriasis and Psoriatic Arthritis: A Systematic Review”, Academic Dermatology 4(1), 1-11. doi: https://doi.org/10.18061/ad.5793
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